New Platform Motifs for Reaction Discovery: Catalysis tools for sustainable synthesis

The introduction of new platform motifs enables the development of myriad new chemical transformations and enhanced understanding of reactivity. In this project we will explore the utility of a new platform motif that has recently been developed in our group, establishing its applicability across a breadth of new catalysis-based molecular transformations. This research contributes to achieving more efficient and sustainable synthesis of complex molecules by shortening overall reaction sequences, and employing highly efficient catalysis methods. The methods are targeted towards structures of interest in medicinal chemistry and organic materials for energy applications, using new chemistry to access desirable molecular properties and taking advantage of designed in modularity and tolerance to enable tuning of properties.

Please see our research group pages for more information about the SynCat group https://syncatdavies.com/

A student on this project will focus on organic synthesis and catalysis methods spanning reaction design and optimisation, structure-reactivity and structure-function relationships; and target applications. Alongside developing their skills and expertise in fields of synthetic organic and transition metal catalysis the student on this project will have opportunities to develop wider skills in physical organic chemistry and mechanistic study, spectroscopy and sustainable chemistry methods as well as in exploring and developing the properties of novel structure arising from this work in collaboration with relevant research groups.

The successful applicant will join a well-equipped laboratory in a new state-of-the-art facility for Chemistry. They are expected to demonstrate strong interest and self-motivation in the subject to be able to take ownership of their project. An enquiring and rigorous approach to research as well as good team-working, observational and communication skills (both presentation and writing skills in English) are also essential. and engage with co-workers in the research group and more widely across the School of Chemistry. Previous research experience in organic synthesis or catalysis is desirable, however training will be provided to help address the successful applicants developmental needs across the PhD programme (technical, scientific and transferable).

The School of Chemistry seeks to attract outstanding, inspirational and talented people, supporting them to succeed and celebrating their success. We value diversity and inclusion and welcome applications from all sections of the community. The School of Chemistry holds an Athena SWAN Bronze Award, in recognition of its work in supporting and transforming gender equality, and the University of Birmingham holds a Race Equality Charter Bronze Award and contributes to the Stonewall Workplace Equality Index. We support flexible working and studying for all.